9H-fluoren-9-ylmethyl piperidin-4-ylcarbamate hydrochloride
9H-fluoren-9-ylmethyl piperidin-4-ylcarbamate hydrochloride
CAS: 221352-86-9
Molecular Formula: C20H23ClN2O2
9H-fluoren-9-ylmethyl piperidin-4-ylcarbamate hydrochloride - Names and Identifiers
| Name | 9H-fluoren-9-ylmethyl piperidin-4-ylcarbamate hydrochloride |
| Synonyms | 4-N-FMOC-AMINO-PIPERIDINE HCL 4-N-Fmoc-amino-piperidine hydrochloride 4-N-Fmoc-amino-piperidine hyrdrochloride 9H-fluoren-9-ylmethyl piperidin-4-ylcarbamate hydrochloride 4-Piperidinylcarbamic acid 9H-fluoren-9-ylmethyl ester monohydrochloride Carbamic acid, 4-piperidinyl-, 9H-fluoren-9-ylmethyl ester, monohydrochloride (9CI) |
| CAS | 221352-86-9 |
| InChI | InChI=1/C20H22N2O2.ClH/c23-20(22-14-9-11-21-12-10-14)24-13-19-17-7-3-1-5-15(17)16-6-2-4-8-18(16)19;/h1-8,14,19,21H,9-13H2,(H,22,23);1H |
9H-fluoren-9-ylmethyl piperidin-4-ylcarbamate hydrochloride - Physico-chemical Properties
| Molecular Formula | C20H23ClN2O2 |
| Molar Mass | 358.87 |
| Boling Point | 520.4°C at 760 mmHg |
| Flash Point | 268.5°C |
| Vapor Presure | 6.28E-11mmHg at 25°C |
| Storage Condition | Sealed in dry,Room Temperature |
| Sensitive | Sensitive to humidity |
| MDL | MFCD01321024 |
9H-fluoren-9-ylmethyl piperidin-4-ylcarbamate hydrochloride - Risk and Safety
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10-21 |
| HS Code | 29333990 |
9H-fluoren-9-ylmethyl piperidin-4-ylcarbamate hydrochloride - Introduction
9H-fluoren-9-ylmethyl piperidin-4-ylcarbamate hydrochloride, also known as 9h-naphthylmethylpiperidine-4-carbonylcarbamic acid chloride hydrochloride, is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: White or off-white crystal or crystalline powder
-Molecular formula: C26H26N2O2 · HCl
-Molecular weight: 439.96g/mol
-Melting Point: 132-136 ℃
-Soluble: Soluble in ethanol, dimethyl sulfoxide and ketone
Use:
- 9H-fluoren-9-ylmethyl piperidin-4-ylcarbamate hydrochloride is commonly used as a protecting group in solid phase synthesis. It is a common amino protecting group, which can be used in the synthesis of amino acids and peptides in chemical synthesis.
-The compound is widely used in the fields of drug development, peptide synthesis and biochemical research.
Method:
- 9H-fluoren-9-ylmethyl piperidin-4-ylcarbamate can be prepared using chemical synthesis methods. A common preparation method is to add 4-amino-piperidine and sodium hydroxide to acetochlor, and then obtain the target product by reduction, acylation and hydrochloric acid salting reaction.
Safety Information:
- 9H-fluoren-9-ylmethyl piperidin-4-ylcarbamate hydrochloride is less toxic and dangerous, but it is still necessary to follow the laboratory safety code of practice.
-Avoid inhaling aerosols and avoid contact with skin and eyes.
-Use appropriate protective equipment during operation, such as lab gloves, safety glasses and lab coats.
-Maintain a dry and well-ventilated environment during storage and handling.
-When using this compound, it is recommended to refer to the chemical safety data sheet and Related Literature to ensure safe operation.
Nature:
-Appearance: White or off-white crystal or crystalline powder
-Molecular formula: C26H26N2O2 · HCl
-Molecular weight: 439.96g/mol
-Melting Point: 132-136 ℃
-Soluble: Soluble in ethanol, dimethyl sulfoxide and ketone
Use:
- 9H-fluoren-9-ylmethyl piperidin-4-ylcarbamate hydrochloride is commonly used as a protecting group in solid phase synthesis. It is a common amino protecting group, which can be used in the synthesis of amino acids and peptides in chemical synthesis.
-The compound is widely used in the fields of drug development, peptide synthesis and biochemical research.
Method:
- 9H-fluoren-9-ylmethyl piperidin-4-ylcarbamate can be prepared using chemical synthesis methods. A common preparation method is to add 4-amino-piperidine and sodium hydroxide to acetochlor, and then obtain the target product by reduction, acylation and hydrochloric acid salting reaction.
Safety Information:
- 9H-fluoren-9-ylmethyl piperidin-4-ylcarbamate hydrochloride is less toxic and dangerous, but it is still necessary to follow the laboratory safety code of practice.
-Avoid inhaling aerosols and avoid contact with skin and eyes.
-Use appropriate protective equipment during operation, such as lab gloves, safety glasses and lab coats.
-Maintain a dry and well-ventilated environment during storage and handling.
-When using this compound, it is recommended to refer to the chemical safety data sheet and Related Literature to ensure safe operation.
Last Update：2024-04-09 15:17:56
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CAS: 221352-86-9
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CAS: 221352-86-9
Tel: 18301782025
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QQ: 3008007409
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